Luca Giovannini, aged five, passed away just 24 hours after complaining he felt sick.
His parents Vickie and Renzo then made the decision to donate some of their son's organs for transplant.
They were given to a two-year-old girl, a two-year-old boy, a 35-year-old mother-of-two and a 34-year-old man.
Renzo, of Wilcott Road, Gatley, Stockport, said: "When the medics were trying to save Luca’s life, I asked a doctor what his chances were of surviving, and he said we were looking at the worst-case scenario.
"It's a scenario which no parent wants to be faced with, but it was at that stage that we discussed organ donation.
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