Statins prevent cancer and reduce death from all causes in heart transplant recipients. The findings were independent of cholesterol levels.
The research was presented at the Heart Failure Congress 2012, 19-22 May, in Belgrade, Serbia. The Congress is the main annual meeting of the Heart Failure Association of the European Society of Cardiology.
Cancer is the leading cause of death late after heart transplantation. Skin cancer is particularly common, but solid organ cancers including colorectal cancer, prostate cancer and lymphoma also occur. The increased rate of cancer in heart transplant recipients may be related to the immune suppression of the patient.
Statins are immunomodulatory drugs and may benefit patients beyond their lipid lowering effects. The current study (abstract P306)
investigated the impact of statin therapy on the occurrence of cancer and death from all causes in heart transplantation recipients.
The study included all 255 patients who underwent heart transplantation at the University Hospital Zurich in Switzerland between 1985 and 2007 and were alive after the first year. The primary endpoint was the occurrence of any cancer and the secondary endpoint was overall survival.
Read more: http://www.sciencecodex.com/statins_prevent_cancer_in_heart_transplant_recipients-91803
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