TWO STUDIES PRESENTED AT THE 37TH ANNUAL ISHLT MEETING & SCIENTIFIC SESSIONS REVEAL EARLY MORTALITY IN LUNG TRANSPLANT RECIPIENTS AND RELATED OUTCOMES IN THE MOMENTUM 3 TRIAL

GLOBE NEWSWIRE

San Diego, April 06, 2017 (GLOBE NEWSWIRE) -- Today at the 37th Annual International Society for Heart and Lung Transplantation (ISHLT) Meeting & Scientific Sessions, researchers shared results during Plenary Session 2: Early Graft Injury Measured by Donor-Derived Cell-Free DNA Predicts Early Mortality in Lung Transplant Recipients. The study showed lung transplant recipients have shorter median survival than other solid organ transplants and better tools to assess risk may allow clinicians to improve the long-term outcomes of patients. The authors of this abstract compared early graft injury (EGI) with cumulative graft injury (CGI) using linear regression and donor derived cell-free DNA (dd-cf-DNA) in patients with and without bronchiolitis obliterans (BOS). They found that elevated counts of dd-cf-DNA during the initial six months of a lung transplant is predictive of increased early mortality and the incidence of severe BOS. Researchers believe dd-cf-DNA may be a method to risk stratify lung transplant recipients. Continue reading
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