Gender plays a role in transplant success


A human heart: the gender of the donor and recipient may be important.
Different hormones produced by men and women may influence the success of organ transplants, a new report finds.

A paper published in the journal Trends in Immunology represents the first time the influence of gender in organ donors and recipients has been assessed. The study, led by surgeon Stefan Tullius from the Brigham and Women’s Hospital in Boston, US, found that some kinds of female donor organs are more likely to be rejected.

The researchers found that in kidney transplants, female organs were more often rejected than male ones – a trend higher among male recipients. In heart transplants, too, female organs were more often rejected, but in this case only in male recipients.

And while the gender bias in transplant rejection was by no means universal, it is considered significant. Continue reading

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